Cholesterol is a yellowish crystalline substance that is an essential structural component of animal membranes. Its name derives from the Ancient Greek word bile, which means "bile-like" or "bile-like." Cholesterol is also referred to as HDL or high-density lipoprotein.
Low-density lipoprotein (LDL)
OxLDL cholesterol is a type of remnant lipoprotein derived from lipoprotein cholesterol. It has a crucial role in atherosclerosis. It acts as an adhesion molecule between cells and recruits macrophages, forming foam cells. Interestingly, OxLDL levels have also been shown to be independent predictors of cardiovascular events in healthy subjects and patients with CAD.
This protein has been implicated in atherosclerosis, but this mechanism is not entirely understood. In obese patients, elevated OxLDL levels may result from low-grade inflammation. In addition, low-grade inflammation may have a role in increased oxidative stress. This indirect mechanism may explain the positive correlation between OxLDL levels and remnant lipoprotein cholesterols.
LDL cholesterol is the type of cholesterol that accumulates in the arteries. When LDL levels are high, it can lead to high blood pressure, stroke, and heart disease. Cholesterol is necessary for the construction of body cells. However, when there are high levels of LDL in the blood, they can clog the arteries and contribute to cardiovascular problems.
High cholesterol can cause various symptoms, including chest pain, a loss of appetite, and a yellow appearance around the eyes. Other symptoms can include weakness or a slurred or shaky gait. If you notice any of these symptoms, it is best to see a doctor.
Cholesterol can affect blood flow to the brain. People with high cholesterol are more likely to suffer from a stroke. High cholesterol levels in the blood can cause plaque to build up in the arteries and restrict the blood flow to the brain. High cholesterol also increases the risk of a blood clot. It can also obstruct the arteries carrying blood to the legs. Leg symptoms can include a heavy feeling or burning sensation. Fatty moles may also form between the skin and muscle.
Although cholesterol is essential for the body, excessive accumulation can lead to serious health issues. Most of these problems relate to the cardiovascular system. Symptoms of high cholesterol often only occur once the disease has advanced.